General Cell Lines and Cell Cultures
ATCC A-549; Lung Carcinoma; Human (Homo sapiens)
A549 cells were isolated from the lung tissue of a White, 58-year-old male with lung cancer. This cell line can be used in cancer, immuno-oncology, and toxicology research.
AdipoGen ODN 1668 (Type B) Endotoxin-free (sterile), 100 ug
MW: 6,383g/mol, Synonyms: CpG ODN TLR9 Agonist: B Type (species: rodent). Unmethylated CG dinucleotides within particular sequence contexts are responsible for the immunostimulatory activity of bacterial DNA. Synthetic oligonucleotides (ODN) that contain such CpG motifs (CpG ODNs) mimic microbial DNA. The innate immune system of vertebrates has the ability to recognize CpG motifs in microbial DNA via the Toll-like receptor (TLR) 9 if the CpG ODN were free of additional immune stimulatory contaminants often present in synthetic commercial CpG ODN preparations designed for molecular biology applications (i.e. PCR). Given that high quality CpG ODNs were used, a close link has been established between the expression of TLR9 on certain immune cell subsets and the modulation of the immune system by CpG DNA.
Genscript Corporation CHO-K1/TRH1 Stable Cell Line
Thyrtropin-releasing hormone receptor1 (TRH1) is a member of G-protein coupled receptor family A This protein is a receptor for Thyrtropin-releasing hormone (TRH) Human TRH1 is expressed in lymphocytes pituitary gland and CNS It can stimulate the releasing of prolactin (PRL) thyrotropin (TSH) TRH1 receptor knockout mice exhibit a slightly reduced growth rate considerable decrease in serum T sub 3 /sub T sub 4 /sub and prolactin levels but no alteration of thyroid-stimulating hormone levels
Genscript Corporation CHO-K1/ADORA2B/G15 Stable Cel
Recombinant CHO-K1 cells stably overexpress human adenosine A2B receptor (ADORA2B) on the surface and contain high levels of G protein G s to couple with the receptor in downstream signaling pathways
Cole-Parmer Extech 480172 3-Prong 120 VAC Line Separator
This AC line separator provides temporary separation of conductors for current measurement with clamp-type meters. Simply plug the separator into a grounded 120 VAC receptacle and then plug it in to your equipment. Turn it on and then measure.
ATCC Human respiratory; syncytial virus; Strain: 18537
Human respiratory syncytial virus strain 18537 is propagated in HEp-2 cells (ATCC CCL-23). This strain was isolated in 1962 from the respiratory secretions of a child with acute respiratory disease seen at Children’s National Hospital in Washington, DC, and was deposited by the National Institute of Allergy and Infectious Diseases (NIAID). It has applications in respiratory disease research.
Eurofins Discoverx PathHunter HCRTR2 Total GPCR Internalization U2OS Cell Line, 2 vials. (93-0730C3)
The PathHunter HCRTR2 Total GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of HCRTR2 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged HCRTR2 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the HCRTR2 receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Mycobacterium smegmatis
Mycobacterium smegmatis strain W-113 is an aerobic, acid fast bacterium.
Sino Biological Mouse ICOS Protein (His Tag), Endotoxin-Free 100µg
A DNA sequence encoding the mouse ICOS (NP_034643.2) (Met1-Gln135) was expressed with a polyhistidine tag at the C-terminus.
ATCC Pfizer Pneumococcal polysaccharide powder Type 20 (d20) 200mg
Purified pneumococcal polysaccharide type 20 is manufactured by Pfizer, Inc. for small quantity distribution by ATCC. The pneumococcal polysaccharide type 20 can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
Eurofins Discoverx Ready-to-Assay OX1 Orexin Receptor Frozen Cells, 2 Vials of Cells. (HTS175RTA)
The Ready-to-Assay OX1 Orexin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. orexins) based activation of HCRTR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses HCRTR1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of HCRTR1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC Quantitative Genomic DNA from; Streptococcus pneumoniae; Strain: 262
Quantitative Genomic DNA from Streptococcus pneumoniae strain 262 [CIP 104340] can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
ATCC HCMEL1274 CUTANEOUS MELANOMA M
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
ATCC Human adenovirus 40 Strain: Dugan
Human adenovirus 40 strain Dugan [79-18025] is propagated in 293 [HEK-293] cells (ATCC CRL-1573). This strain was isolated in 1979 from the feces of a human with infantile gastroenteritis. This product is whole-genome sequenced has applications in enteric and infectious disease research.
ATCC HCT116-SLC27A2-KO-c7; Colorectal carcinoma; Human (Homo sapiens)
The HCT116-SLC27A2-KO-c7 cell line contains a -11 deletion/+1 bp insertion in SLC27A2 gene and combined with the parental cell line and other HCT116 derivatives can be used in cancer drug screening.